Denis Wirtz,PHD

Vice Provost for Research; Theophilus Halley Smoot Professor of Chemical and Biomolecular Engineering

Specialization: 3D cell motility, ageing and cancer, digital pathology


Johns Hopkins Whiting School of Engineering

3400 N. Charles Street

Croft Hall 116

Baltimore, MD 21218


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Wirtz studies the biophysical properties of healthy and diseased cells, including interactions between adjacent cells and the role of cellular architecture on nuclear shape and gene expression.

Cell biophysics, single molecule manipulation, intracellular particle trafficking, instrument development, tissue engineering, and nanotechnology in biology and medicine are some of Dr. Wirtz’ research interests. He was elected as a fellow of the American Association for the Advancement of Science for his contributions to cell micromechanics and cell adhesion. He also was distinguished for his development and application for particle tracking methods to probe the micromechanical properties of living cells in normal conditions and disease state.


To advance neuroscience discovery by uniting neuroscience, engineering and computational data science to understand the structure and function of the brain.