Neuronal selectivity, a neuron’s ability to respond to specific stimuli, is critical to determine how the neuron behaves to different cues. A team of researchers at Johns Hopkins University, including Kavli NDI members, Ingie Hong, Richard Huganir, Seth Blackshaw, Dwight E. Bergles and Solange P. Brown have identified a subtype of receptors, Calcium Permeable AMPA receptors, that are responsible for controlling neuronal selectivity.