The basic structure of the cortical circuits is similar across functional areas, yet different classes of cortical projection neurons, the major cell type in the cortex, are specialized to send distinct messages out of the cortex to target brain regions. Using a bottom-up approach, we are determining how these different messages are generated, what they mean in brain processing, and how abnormalities in these processes contribute to neurologic and psychiatric diseases.
Solange Brown,MD, PHD
Associate Professor of Neuroscience
Specialization: Functional organization of neocortical circuits
Johns Hopkins University School of Medicine
725 N. Wolfe Street
Baltimore, MD 21205
The long-term goal of our work is to understand the functional organization of the mammalian neocortex in the healthy brain and the alterations in circuit properties that underlie neurologic and psychiatric disease.
To advance neuroscience discovery by uniting neuroscience, engineering and computational data science to understand the structure and function of the brain.