Therefore, a fundamental question in neuroscience is to understand how experience alters synapses in the brain. The Lee lab tackles this question using multidisciplinary approaches combining electrophysiological, molecular/biochemical, imaging, and optogenetic methods to study the changes that occur at synapses when a sensory modality is lost. Furthermore, we have been applying the current knowledge on the biological basis of synaptic plasticity to devise ways to treat memory disorders, especially the Alzheimer’s disease, which begins as a loss in the ability to form new memories. 

Link to a video is here:

https://www.youtube.com/watch?v=dk57dbF_aJ8

Link to an NPR coverage of my research is here:

http://www.npr.org/sections/health-shots/2014/02/05/272092118/seeing-less-helps-the-brain-hear-more