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Cross-modal sensory deprivation promotes adult cortical plasticity

Plasticity of thalamocortical (TC) synapses is limited in adults. Rodriguez et al. demonstrate that a brief period of deafening adults recovers LTP at TC synapses in visual cortex and accelerates ocular dominance plasticity. These results suggest that cross-modal sensory deprivation may be an effective way to promote adult cortical plasticity.

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